The Gen-F GTS features a 6.2-litre supercharged LSA V8 engine which provides 430 kW of power and 740 Nm of torque.

To assist with its cooling requirements, the GTS is fitted with a stacked plate engine oil cooler and a stand-alone water-to-air charge-air cooling system. Unique tail shafts cater for the higher torque loads and the rear differential helps transfer all of the power to ground.

At the time of its release and up untill the release of the HSV Gen-F GTS/R, the GTS was the most powerful car ever produced in Australia. Like the ClubSport, the GTS is available in both a six-speed manual and a six-speed automatic transmission and it also features 20-inch alloy wheels. Due to the increase in power the GTS has a larger brake package than the ClubSport, also for the sportier look a larger rear spoiler. The GTS is also equipped with generation 3 magnetic ride control or MRC. There are three modes for the MRC, tour, sport/performance and track. The GTS is equipped with a driver preference dial that has four modes to adjust the bi-model exhaust and MRC, these are Tour, Sport, Performance, Track.